Research Studies by Dr. Farr

The following studies are conducted by Dr. Farr. An updated list of current studies and enrollment status can be found at clinicaltrials.gov. For more information about active studies, please email jackfarrresearch@orthoindy.com.

Enrolling Studies:

  • A Post Market,Single Blind, MultiCenter, Randomized, Controlled Trial of Hymovis Intra-Articular Injections in Active Subjects with Knee OsteoArthritis (Phase IV)
  • Evaluation of the ReNu Amniotic Suspension Allograft after Marrow Stimulation in the Treatment of Osteochondral Defects
  • A randomized, placebo-controlled, patient and investigator blinded, Proof of Concept study investigating the safety, tolerability and preliminary efficacy of multiple intra-articular LNA043 injections in regenerating the articular cartilage of the knee in patients with articular cartilage lesions
  • Justifying Patellar Instability Treatment by Early Results (JUPITER)
  • MOCA (Metrics of Osteochondral Allografts) REGISTRY

Surgical Outcome Studies:

  • Anterior Cruciate Ligament Reconstruction
  • Anteromedialization (AMZ)
  • MACI Implantation/ Articular Cartilage Implantations
  • Fresh Osteochondral Shell Transplantation
  • High Tibial Osteotomy
  • Medial Patellofemoral Ligament Reconstructions
  • Meniscal Transplantation
  • Patellofemoral Arthroplasty
  • Total Knee Arthroplasty

Closed to Enrollment:

  • Determining the Minimal Clinical Important Difference (MCID) and Patient Acceptable Symptomatic State (PASS) for Patients Undergoing Articular Procedures of the Knee
  • Multi-Center Experience with ACI in the Patellofemoral Compartment
  • Decreased Re-intervention Rate with Collagen Membrane ACI
  • A Prospective Double Blinded, MultiCenter, Randomized, Controlled Trial to Evaluate Mechanical Debridement vs. Radiofrequency-Based Debridement in the Treatment of Articular Cartilage Lesions
  • NeoCart: A Randomized Comparison of Neocart to Microfracture for the Repair of Articular Cartilage Injuries in the Knee
  • An Investigation of ReNu™ Knee Injection: Monitoring the Response of Knee Function and Pain in Patients with OsteoArthritis
  • Longitudinal Histologic Assessment and Gen Expression Profiling of Healing Cartilage Defects
  • Prospective, MultiCenter Single Arm Pilot Study To Evaluate Symptom Relief in Patients with Medial Knee OsteoArthritis (OA) Treated with the KineSpringÒ Knee Implant for Load Reduction (SOAR)
  • Knee Creations SCPÒ Observational Cohort Follow-up Study
  • Prospective Efficacy Evaluation of Subchondroplasty™ for the Treatment of Defects Associated with Tibial Marrow Lesions
  • Validity of an Interactive Technique for Collecting Patient Reported Outcomes of Orthopaedic Procedures
  • A Post-Market, Longitudinal Data Collection Study of Articular Cartilage Defects of the Knee Treated with Denovo® NT Natural Tissue Graft Protocol#CSU2010-22B
  • A Post Market Study to Evaluate the Chondrofix Osteochondral Allograft Utilized for Treatment of Subjects with Cartilage Lesions in the Knee
  • AANA: Acute Complications of Knee and Shoulder Arthroscopy
  • A Feasibility Study to Determine the Up-Regulation of Anti-inflammatory Cytokines in Whole Blood From Patients with Osteoarthritis
  • A Multicenter, Randomized, Pivotal Study to Evaluate the Safety and Efficacy of the Cartilage Autograft Implantation System (CAIS) for the Surgical Treatment of Articular Cartilage Lesion of the Knee
  • A Long-Term Follow-up Study of Chondrogen™ Adult Universal Cell Delivered by Intra-articular Injection Following Meniscectomy in Patients 18-60 Years
  • Regeneration Technologies, Inc. Registry of Biocleanse® Meniscus Transplants
  • A Post Market Study of Articular Cartilage Defects of the Knee Treated with DeNovo® NT, Natural Tissue Graft.
  • An Open-Label Phase I/II Pilot Study to Evaluate Articular Cartilage Defects of the Knee with a Neocartilage Implant
  • Collection of Specimens from Joint Replacement Surgery for In-Vitro Osteoarthritis Research
  • Evaluation Outcomes After Standard of care Operative and Non-operative Management of the Knee 20 Year Follow-up